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Consequently, the metabolite is liable for about twenty% of sildenafil's motion. Sildenafil is excreted as metabolites predominantly in the feces (about 80% of administered oral dose) also to a lesser extent in the urine (all around 13% with the administered oral dose). If taken with a substantial-fat food, absorption is decreased; enough time taken to achieve the maximum plasma focus raises by all over 1 hour, and the utmost concentration alone is lowered by almost one-third.[fifty two]

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